Simplicef™ Tablets
Generic Name:
Cefpodoxime proxetil
An oral cephalosporin antibiotic used to treat many common bacterial infections in dogs and cats (ex. ear, bladder and skin infections). Typically, you only need to give cefpodoxime once daily. Cefprodoxime is available as 100 mg and 200 mg tablets or as an oral suspension.
- 3rd generation cephalosporin; an antibiotic
- Given by mouth
- Useful broad spectrum antibiotic most often prescribed for common and uncomplicated infections
- Especially useful against many skin infections
- Use with caution in pets with kidney failure or a history of seizures
- Use with caution in breeding, pregnant or nursing animals
- Pets whom have had previous allergic reactions to penicillin, other cephalosporins or antibiotics
Give medication as directed by your veterinarian. It is usually given once a day.
Missed doses reduce the effectiveness of therapy.
Read and follow the label carefully.
Give the exact amount prescribed and only as often as directed.
Give this medication for as long as your veterinarian directs.
For liquids, shake well before accurately measuring the dose.
May be given on a full or empty stomach.
Ideally, give the medication at the same time daily.
If a dose is missed, give it as soon as you can. If it is time already for the next dose, skip the missed dose and go back to the normal schedule. Do not give two doses at the same time.
Talk to your veterinarian about:
- When will your pet need to be rechecked
- What tests may need to be performed prior to and during treatment with this drug
- Risks and benefits of using this drug
Tell your veterinarian about:
- If your pet has experienced side-effects on other drugs/products
- If your pet has experienced digestive upset now or ever
- If your pet has experienced kidney disease now or ever
- If your pet has experienced any other medical problems or allergies now or ever
- All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medicines can be given together.
- If your pet is pregnant or nursing or if you plan to breed your pet
Store tablets and powder in a tight, light resistant, childproof container in a cool, dry place at room temperature away from heat and direct sunlight.
Once reconstituted, the oral suspension is stable for two weeks (refrigeration is recommended). Shake well before using.
Keep this and all medication out of reach of children and pets.
Call your physician immediately if you accidentally take this product.
Pet owners who are allergic to penicillin and/or other antibiotics should use caution when handling this drug.
- This medication is usually well tolerated by dogs and cats and is commonly used for several weeks
- Vomiting, diarrhea and loss of appetite may be experienced
- If you notice anything unusual, contact your veterinarian
- These drugs may interact with cefpodoxime: H2 antagonists (ranitidine, cimetidine), omeprazole and antacids.
Contact your veterinarian if pet eats more than the prescribed amount.
As with all prescribed medicines, cefpodoxime should only be given to the dog/cat for which it was prescribed. It should be given only for the condition for which it was prescribed.
Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.
This is just a summary of information about cefpodoxime. If you have any questions or concerns about cefpodoxime or the condition it was prescribed for, contact your veterinarian.