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Deramaxx Chew Tabs

Deramaxx Chew Tabs by Novartis Direct

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Deramaxx® Chewable Tablets

Generic Name:


General Description:

Deracoxib is an oral nonsteroidal anti-inflammatory drug (NSAID) used in dogs to control pain and inflammation due to osteoarthritis or following bone or dental surgery. While deracoxib is not a cure for osteoarthritis, it can control the pain and inflammation of osteoarthritis and improve your dog's mobility. This medication may be given with or without food, although with food is preferable. Response varies but in most dogs, improvement can be dramatic. Deracoxib is available in 12 mg, 25 mg, 75 mg and 100 mg flavored chewable tablets.

What is this drug?
  • Deracoxib is a nonsteroidal anti-inflammatory drug (NSAID) of the COX2 inhibitor class
  • Given by mouth
  • Available as flavored tablets to make administration more convenient
Reasons for prescribing?
  • Used to control pain and inflammation (soreness) due to osteoarthritis in dogs [signs include limping or lameness, decreased activity or exercise (reluctance to stand, climb stairs, jump or run, or difficulty in performing these activities), stiffness or decreased movement of joints]
  • For the control of postoperative pain and inflammation associated with bone or dental surgery in dogs
What dogs/cats should not take this medication?
  • Deracoxib should be given to dogs only
  • Has had an allergic reaction to the active ingredient deracoxib
  • Has had an allergic reaction (such as hives, facial swelling, or red or itchy skin) to aspirin or other NSAIDs
  • Is presently taking aspirin, other NSAIDs, or corticosteroids (unless directed by your veterinarian)
  • Has bloody stool or vomit or a bleeding disorder (for example Von Willebrand's disease)
  • Has a pre-existing kidney or liver condition
  • Has any condition predisposing to dehydration
  • Is anorexic (loss of appetite)

Deracoxib should be given according to your veterinarian's instructions. Your veterinarian will tell you what amount of deracoxib is right for your dog and for how long it should be given. Do not change the way you give deracoxib tablets to your dog without first speaking with your veterinarian.

Deracoxib should be given by mouth and may be given with or without food, although with food is preferable.

The postoperative orthopedic pain dose is a higher dose; administration at this dose should not exceed 7 days total, including the days the patient is administered deracoxib while in the hospital.

If deracoxib is discontinued or not given as directed by your veterinarian, your dog's pain and inflammation may return.

While deracoxib is not a cure for osteoarthritis, it can control the pain and inflammation of osteoarthritis and improve your dog's mobility. Response may vary from dog to dog but can be quite dramatic.

Deracoxib tablets may need to be given on a periodic basis for the animal's lifetime. Use the lowest dose to provide adequate relief. Always consult with your veterinarian before altering the dose.

What to tell/ask veterinarian before giving medication?

Talk to your veterinarian about:

  • The orthopedic or dental surgery your dog will undergo
  • What tests might be done before surgery is performed or deracoxib tablets are prescribed
  • The signs of pain or inflammation that may occur after surgery
  • Normal events that can be expected after your dog undergoes surgery
  • The proper amount of exercise after surgery to aid recovery
  • The signs of osteoarthritis you have observed (for example, limping or stiffness)
  • The importance of weight control, physical therapy and exercise in the management of osteoarthritis
  • How often your dog may need to be examined by your veterinarian
  • The risks and benefits of using deracoxib tablets

Tell your veterinarian about:

  • Any side effects your pet has experienced from deracoxib or other NSAIDs, such as aspirin
  • Any digestive upset (vomiting and/or diarrhea) your dog has had
  • Any liver and kidney disease your dog has had
  • A bleeding disorder (for example, Von Willebrand's disease)
  • Any other medical problems or allergies that your dog has now or has had
  • All medicines that you are giving your dog or plan to give your dog, including those you can get without a prescription
  • If your dog is pregnant, nursing or if you plan to breed your dog
Storage and Warnings:

Store in a tight, light resistant, childproof container at room temperature away from heat and direct sunlight.

For use in dogs only. People should not take deracoxib. Keep deracoxib and all medicine out of reach of children.

Call your physician immediately if you accidentally take deracoxib.

Potential side effects?

Deracoxib, like all other drugs, may cause some side effects in individual dogs. These are normally mild, but rare serious side effects have been reported in dogs taking nonsteroidal anti-inflammatory drugs (NSAIDs) including deracoxib. Liver and kidney problems have been reported. Serious side effects can, in rare situations, result in death. It is important to stop the medication and contact your veterinarian immediately if you think your dog may have a medical problem or side effect while on deracoxib. If you have additional questions about possible side effects, talk with your veterinarian or call 1-800-637-0281.

Look for the following side effects that may indicate that your dog is having a problem with deracoxib or may have another medical problem:

  • Vomiting
  • Decrease in appetite
  • Change in behavior, such as depression, restlessness, aggression or apprehension
  • Change in bowel movements such as diarrhea or change in stool color (black, tarry or bloody)
  • Change in drinking or urination
  • Yellowing of gums, skin or whites of the eyes (jaundice)
Can this drug be given with other drugs?
  • Deracoxib should not be given with other NSAIDs (ex. aspirin, carprofen or etodolac) or corticosteroids (ex. prednisone).

Contact your veterinarian immediately if your dog eats more than the prescribed amount of deracoxib.

What else should I know?

This sheet provides a summary of information about deracoxib. If you have any questions or concerns about deracoxib, postoperative orthopedic and dental pain and inflammation, or osteoarthritis, talk to your veterinarian.

As with all prescribed medicines, deracoxib should only be given to the dog for which it was prescribed. It should be given to your dog only for the condition for which it was prescribed. It is important to periodically discuss your dog's response to deracoxib at regular check ups.

Your veterinarian will best determine if your dog is responding as expected and if your dog should continue receiving deracoxib.


Common Drug Name

Common Brand Names
No generic products available.

Store at room temperature in a tight, childproof container. The chewable form of the drug is appealing to pets and children. Store in a secure area to prevent an accidental overdose.

Deracoxib is a non-steroidal anti­inflammatory drug (NSAID) of the coxib class.
Deracoxib is for use in dogs for the treatment of pain and inflammation associated with osteoarthritis, including hip dysplasia. It is also approved for the control of postoperative pain associated with soft tissue and orthopedic surgeries. It may also be used in the treatment of certain cancers (transitional cell carcinomas) of the urinary bladder.
Do NOT use in cats.

Dose and Administration
Always follow the dosage instructions provided by your veterinarian. If you have difficulty giving the medication, contact your veterinarian.
Deracoxib is given by mouth, preferably with food.
For long-term treatment, use the lowest dose needed to provide relief. For arthritic conditions, deracoxib may need to be given on a periodic basis for the animal’s lifetime. 
If you miss a dose, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give 2 doses at once.
This medication should only be given to the pet for whom it was prescribed. 

Possible Side Effects
The most common side effect of NSAIDs is stomach upset, but stomach ulcers may develop, in which case you may see loss of appetite; vomiting; diarrhea; dark, tarry or, bloody stools; or constipation. Side effects involving the kidney include increased thirst and urination, or changes in the urine color or smell. Side effects involving the liver include jaundice (yellowing of the gums, skin, or eyes). Side effects of the skin include hives, swelling of the face, itchiness, redness or sores. Other side effects may include pale gums, lethargy, incoordination, seizures, or behavioral changes. If any of these side effects are observed, stop treatment and contact your veterinarian.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Not for use in animals who are hyper­sensitive (allergic) to deracoxib (Deramaxx), carprofen (Novox or Rimadyl), aspirin, etodolac (EtoGesic), meloxicam (Metacam), firocoxib (Previcox), tepoxalin (Zubrin), or other NSAIDs.
The safety of the drug has not been determined in breeding, pregnant, or lactating animals (female animals nursing their young), or in nursing puppies.
Use with extreme caution and continued monitoring in geriatric animals and those with dehydration or stomach, intestinal, liver, heart, or blood disorders.
Provide access to fresh, clean water at all times to help avoid dehydration.
Consult with your veterinarian regarding the physical examinations and laboratory testing necessary prior to and during treatment with deracoxib.

Drug, Food, and Test Interactions
Consult your veterinarian before using deracoxib with any other medications, including vitamins and supplements, other NSAIDs (e.g., aspirin, etodolac (EtoGesic), carprofen (Novox or Rimadyl), tepoxalin (Zubrin), firocoxib (Previcox), meloxicam (Metacam)); steroids (e.g., prednisone, prednisolone, dexamethasone, triamcinolone, Medrol); methotrexate, diuretics (e.g., furosemide (Lasix)); phenobarbital; enalapril; phenylpropanolamine; or certain antibiotics (aminoglycosides such as gentamicin), and phenobarbital, since interactions may occur. 

Signs of Toxicity/Overdose
May see loss of appetite, vomiting, diarrhea, dark or tarry stools, bloody stools, constipation, increased thirst, increased urination, pale gums, jaundice (yellowing of gums, skin, or eyes), lethargy, increased respiration (fast or heavy breathing), incoordination, seizures, or behavioral changes.
An overdose or toxicity could be fatal.
If you know or suspect your pet has had an overdose, or if you observe any of these signs in your pet, contact your veterinarian immediately.
Keep this and all other medications out of the reach of children and pets.

This information may not cover all possible uses, directions, side effects, precautions, allergic reactions, drug interactions, or withdrawal times. Always consult your own veterinarian for specific advice concerning the treatment of your pet.

Customer Reviews

Average Customer Rating: (Excellent) based on 1 review
Write an online review and share your thoughts with other customers.

551 of 914 found the following review helpful:
5 Stars
by Richard from Phoenix, AZ on Jun 6, 2016

My German shepherd (Lucy) is now 11 years old. This dog has had a very active life. I enjoy riding and had raced mountain bikes where my dog would run 10-15 miles a night at least 3-5 nights a week. Obviously she has slowed down and now in her older age has been slower getting up and not wanting to go very far. With this Deramaxx after the first couple days the difference was extraordinary... It was as though my dog had gone back 6 years. I still try to take it easier with her but almost as though she doesn't want me too. Thank you for making it possible for my best friend and I to still enjoy life together.

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