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Revolution for Cats

Revolution for Cats by Zoetis

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Revolution's Generic Name:


Revolution General Description:

A safe and simple monthly topical medication to protect your pet from heartworms, fleas, sarcoptic mange, ear mites and ticks. Selamectin also kills roundworms and hookworms in cats. Because of the low-volume dosage size, the solution can be applied in one spot. It is non-greasy and quick-drying. Use Selamectin on dogs older than 6 weeks or cats older than 8 weeks of age. Selamectin is sold in packs containing 3, 6 or 12 single dose tubes. Your veterinarian will help you choose the pack best-suited to your pet.

What is Revolution for Cats?
• A parasiticide that fights both internal and surface parasitic infections
• Applied topically

Reasons for prescribing heartworm prevention:
• Dogs: Kills adult fleas and prevents flea eggs from hatching for one month, prevent and control flea infestations; prevents heartworm disease; treats and controls ear mites, sarcoptic mange; control of tick infestations
• Cats: Kills adult fleas and prevents flea eggs from hatching for one month, prevent and control flea infestations; prevents heartworm disease; treats and controls ear mites; treatment and control of roundworms and hookworms

What dogs/cats should not take Revolution for Cats?
• Dogs younger than 6 weeks of age or cats younger than 8 weeks of age
• Sick, debilitated or underweight animals
• Use with caution if pet's skin is broken or irritated
• Safe to use on breeding animals and on pregnant and nursing females
• If your pet has had an allergic reaction to selamectin or like products


Read and follow the label carefully. Reminder stickers are included to place on your calendar for each of the months following the date of the first dose.

At your veterinarian's discretion, a blood test may be necessary to determine the presence of an existing heartworm infection in your pet.

Administer the entire contents of a single dose tube (or two tubes for dogs weighing >130 pounds) topically. Part the hair on the animal's back at the base of the neck in front of the shoulder blades. Place the tube tip on the skin and squeeze the tube emptying the contents directly onto the skin in one spot. Ensure that the tube is empty. Do not massage product into the skin.

Do not give orally. Do not apply to broken skin or onto wet hair coat.

To maximize the effectiveness, do not bathe the animal or allow the pet to swim for 2 hours.

Call ahead for refills.

Flea control: Administer at monthly intervals starting one month before fleas become active until the end of flea season.

Heartworm prevention: Administer monthly year-round, or at least within one month after the first exposure to mosquitoes, and monthly thereafter until one month after mosquito season ends. If selamectin replaces another type of heartworm preventive, give the first dose within 30 days of the last dose of the previous product.

Ear mites: Administer once as a single dose. Some dogs may require a second monthly dose. Monthly use will control any subsequent infections. Cleaning the infested ears is recommended.

Sarcoptic mange in dogs: Administer once as a single dose. Some dogs may require a second monthly dose. Monthly use will control any subsequent infections.

Tick control in dogs: Apply monthly. In heavy tick infestations, complete efficacy may not be achieved in one dose. An additional dose may be administered two weeks after the first, with monthly dosing continued thereafter.

Roundworms and hookworms in cats: Apply once as a single dose. Humans can contract these parasites from animals. Ensure everyone in your household maintains good personal hygiene.

What if a dose is missed?

If a dose is missed and a monthly interval between dosing is exceeded, immediately apply selamectin and resume monthly dosing to reduce the opportunity for the development of adult heartworms. Do not give two doses at the same time.

What to tell/ask veterinarian before giving Revolution for Cats?

Talk to your veterinarian about:
• When will your pet need to be rechecked
• What tests may need to be performed prior to and during treatment with this drug
• What are the risks and benefits of using this drug

Tell your veterinarian about:
• If your pet has experienced side-effects on other drugs/products
• If your pet has experienced any other medical problems or allergies now or ever
• All medicines and supplements that you are giving your pet or plan to give your pet, including those you can get without a prescription. Your veterinarian may want to check that all of your pet's medicines can be given together.

Revolution Storage and Warnings:

Store below 30°C (86°F).

Discard empty tubes in your ordinary household garbage. Do not expose to heat or flame.

Keep this and all medication out of reach of children and pets. Not for human use. May be irritating to skin and eyes. Wash hands after use and wash off any product in contact with the skin immediately with soap and water.

Call your physician immediately if you accidentally take this product.

Potential side effects:
• Stiff hair, clumping of hair or hair discoloration, hair loss, skin irritation or a slight powdery residue may be seen at the treatment site. These effects are temporary and will not affect the safety or effectiveness of the product.
• Side effects are rare, but may include decreased appetite, drooling, vomiting, diarrhea, muscle tremors, fever and rapid breathing
• If these symptoms persist or you notice anything else unusual, contact your veterinarian

Can this drug be given with other drugs?
• There are no known drug interactions with selamectin.
• Do not use with other topical flea and tick control products
• If your pet experiences any unusual reactions when taking multiple medications, contact your veterinarian.


Contact your veterinarian immediately if pet receives more than the prescribed amount.

What else should I know about Revolution for Cats?

Notify your veterinarian if your animal's condition does not improve or worsens despite this treatment.

As with all prescribed medicines, selamectin should only be given to the pet for which it was prescribed. It should be given only for the condition for which it was prescribed.

This is just a summary of information about selamectin. If you have any questions or concerns about selamectin or the condition it was prescribed for, contact your veterinarian.



Selamectin (Revolution)

Generic Name
No generic products are available.

Common Brand Names

Store below 86°F.

Dogs: Selamectin is a heartworm preventive and used to prevent and control flea infestations. It is approved for the treatment and control of ear mites, sarcoptic mange (scabies), and the control of  infestations with Dermacentor variabilis (American Dog) ticks.
Cats: Selamectin is a heartworm preventive and used to prevent and control of flea infestations. It is used for the treatment and control of roundworms, hookworms, and ear mite infestations.

Dose and Administration
Always follow the dosage instructions provided by your veterinarian.
Selamectin is applied topically to the skin, following the manufacturer?s directions.
Do not rub into the skin or apply when the hair is wet.
Do not give orally (by mouth).
Dose and frequency of application depend upon the reason for use.
For heartworm prevention, follow your veterinarian?s directions on when to apply this medication. If advised to give it seasonally, remember to give it during and 1 month beyond the mosquito season, preferably on the same date each month. The tablet kills the parasites acquired during the previous month. (The tablet given May 1st treats exposures to heartworm during the month of April.)
If a dose is missed, immediately apply the product, resume applying the medication every 30 days (once a month), and notify your veterinarian.
For ear mites, cleansing of the ear before using the product is recommended, but not necessary
This medication should only be given to the pet for whom it was prescribed.

Possible Side Effects
Side effects are rare but may include loss of appetite, salivation (drooling), diarrhea, vomiting, muscle tremors, fever, and rapid breathing.
May see stiff hair, clumping of hair, hair discoloration, hair loss, skin irritation, or a powdery residue at the application site.
If your pet experiences an allergic reaction to the medication, signs may include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If you observe any of these signs, contact your veterinarian immediately.

Do not use on animals that are hypersensitive (allergic) to it.
Use with caution if the pet?s skin is broken or irritated, as this product contains alcohol and may be irritating.
Avoid getting the product on human skin, and avoid contact with the application site while it is still wet. Wash hands after use, and if the product gets on human skin, wash it off immediately.
Prevent oral ingestion of the medication, or contact with the eye.
Wait at least 2 hours after application before bathing the animal or allowing the pet to swim.
Do not use on puppies less than 6 weeks of age or kittens less than 8 weeks of age. 
Use with caution in sick, weak, or underweight animals. 
Safe to use on breeding animals and pregnant and nursing females. 
Consult your veterinarian regarding heartworm testing your pet prior to and during treatment with this medication.
Some intestinal parasites may be zoonotic (able to infect humans). Consult your veterinarian or physician on how to prevent human infection and reinfection of your pet.
Dispose of tubes in regular household refuse.
Do not expose to flame, the product is flammable.

Drug and Food Interactions
Notify your veterinarian of any other medications, including vitamins and supplements, your pet is taking while your pet is receiving selamectin.
Do not use with other topical flea/tick control products.
No known drug or food interactions.

Signs of Toxicity/Overdose
Rare. May see any of the above side effects. Contact your veterinarian if you observe any of these effects.
Keep this and all other medications out of the reach of children and pets.

This information may not cover all possible uses, directions, side effects, precautions, allergic reactions, drug interactions, or withdrawal times.  Always consult your own veterinarian for specific advice concerning the treatment of your pet.


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